Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster

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Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster

This study investigated the genotoxicity of Lapachol (LAP) evaluated by wing spot test of Drosophila melanogaster in the descendants from standard (ST) and high bioactivation (HB) crosses. This assay detects the loss of heterozygosity of marker genes expressed phenotypically on the fly's wings. Drosophila has extensive genetic homology to mammals, which makes it a suitable model organism for ge...

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ژورنال

عنوان ژورنال: Genetics and Molecular Biology

سال: 2010

ISSN: 1678-4685,1415-4757

DOI: 10.1590/s1415-47572010005000070